What type of anemia is commonly associated with chronic kidney disease?

Anemia of chronic disease is commonly associated with chronic kidney disease for several reasons. Chronic kidney disease leads to a decrease in erythropoietin production, which is a hormone produced by the kidneys that stimulates red blood cell production in the bone marrow. As the kidneys become less able to produce adequate amounts of erythropoietin, the resulting decrease in red blood cell production can contribute to anemia.

Additionally, in chronic kidney disease, there is often an inflammatory response that can cause changes in iron metabolism and the utilization of iron for hemoglobin synthesis. This impaired iron mobilization further exacerbates the anemia seen in patients with chronic kidney disease.

Overall, the combination of inadequate erythropoietin production, altered iron metabolism, and the presence of inflammation make anemia of chronic disease the most prevalent type of anemia seen in individuals with chronic kidney disease. Iron deficiency anemia, aplastic anemia, and pernicious anemia have different underlying causes and mechanisms that are not primarily linked to the changes associated with chronic kidney disease.