What is the potential consequence of a deficiency in factor XI?

What is the potential consequence of a deficiency in factor XI?

• A. Hemophilia A
• B. Hemophilia B
• C. Hemophilia C
• D. Von Willebrand disease

Answer: (C)

A deficiency in factor XI is associated with Hemophilia C, which is characterized by a bleeding tendency due to the impaired ability to form blood clots effectively. Unlike Hemophilia A and Hemophilia B, which are caused by deficiencies of factor VIII and factor IX, respectively, Hemophilia C results from a deficiency in factor XI, which is part of the intrinsic pathway of the coagulation cascade. Individuals with Hemophilia C may experience bleeding episodes, but the severity is often less pronounced compared to the other forms of hemophilia. The recognition of factor XI deficiency is crucial, as it may also be more prevalent in certain populations, such as Ashkenazi Jews. Understanding this distinction is essential for proper diagnosis and management of bleeding disorders, as the underlying factor deficiencies directly impact the clinical presentation and treatment approaches.

A deficiency in factor XI is associated with Hemophilia C, which is characterized by a bleeding tendency due to the impaired ability to form blood clots effectively. Unlike Hemophilia A and Hemophilia B, which are caused by deficiencies of factor VIII and factor IX, respectively, Hemophilia C results from a deficiency in factor XI, which is part of the intrinsic pathway of the coagulation cascade.

Individuals with Hemophilia C may experience bleeding episodes, but the severity is often less pronounced compared to the other forms of hemophilia. The recognition of factor XI deficiency is crucial, as it may also be more prevalent in certain populations, such as Ashkenazi Jews.

Understanding this distinction is essential for proper diagnosis and management of bleeding disorders, as the underlying factor deficiencies directly impact the clinical presentation and treatment approaches.