How can chronic kidney disease affect hematology?

How can chronic kidney disease affect hematology?

• A. It can increase red blood cell count.
• B. It can lead to anemia due to decreased erythropoietin production.
• C. It enhances iron absorption.
• D. It decreases white blood cell production.

Answer: (B)

Chronic kidney disease (CKD) has a significant impact on the hematologic system, primarily due to its effect on erythropoietin production. Erythropoietin is a hormone produced by the kidneys that stimulates the bone marrow to produce red blood cells. In individuals with CKD, the kidneys lose their ability to produce sufficient amounts of erythropoietin. This deficiency leads to a reduced production of red blood cells, which ultimately results in anemia. Anemia in the context of chronic kidney disease is often characterized by symptoms such as fatigue, weakness, and pallor, which can significantly affect a patient’s quality of life. Anemia in CKD is multifactorial, but the predominant mechanism is indeed the decreased erythropoietin production due to compromised renal function. The other choices do not accurately reflect the physiological changes associated with CKD. For instance, CKD does not typically lead to an increased red blood cell count, nor does it enhance iron absorption; instead, patients may experience iron deficiency due to poor dietary intake or chronic blood loss. Additionally, while CKD can affect white blood cell functions due to various factors, it is not primarily noted for directly decreasing white blood cell production as a central pathoph

Chronic kidney disease (CKD) has a significant impact on the hematologic system, primarily due to its effect on erythropoietin production. Erythropoietin is a hormone produced by the kidneys that stimulates the bone marrow to produce red blood cells. In individuals with CKD, the kidneys lose their ability to produce sufficient amounts of erythropoietin. This deficiency leads to a reduced production of red blood cells, which ultimately results in anemia.

Anemia in the context of chronic kidney disease is often characterized by symptoms such as fatigue, weakness, and pallor, which can significantly affect a patient’s quality of life. Anemia in CKD is multifactorial, but the predominant mechanism is indeed the decreased erythropoietin production due to compromised renal function.

The other choices do not accurately reflect the physiological changes associated with CKD. For instance, CKD does not typically lead to an increased red blood cell count, nor does it enhance iron absorption; instead, patients may experience iron deficiency due to poor dietary intake or chronic blood loss. Additionally, while CKD can affect white blood cell functions due to various factors, it is not primarily noted for directly decreasing white blood cell production as a central pathoph